MAVENCLAD™ (cladribine tablets) │ EMD Serono
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Monitoring

MAVENCLAD™’S MONITORING INCLUDES PRETREATMENT SCREENING AND PERIODIC MONITORING OF LYMPHOCYTE COUNTS1

Monitoring Lymphocyte

Lymphocyte counts must be:

  • Normal before initiating MAVENCLAD in year 1
  • At least 800 cells/mm³ (i.e., Grade 0 or 1) before initiating MAVENCLAD in year 2

The treatment course in year 2 can be delayed for up to 6 months to allow for lymphocyte
recovery. If recovery takes more than 6 months, the patient should stop taking MAVENCLAD.

Should lymphocyte counts drop below 500 cells/mm³, active monitoring is recommended until values increase above 500 cells/mm³.

Screening prior to treatment initiation:

Monitoring Screening

Learn more about MAVENCLAD

 

Demonstrated efficacy

MOA

Safety and tolerability profile

  

 

Explore MAVENCLAD’s efficacy.

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Understand MAVENCLAD’s MOA.

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Learn about MAVENCLAD’s safety and
tolerability profile.

Learn more

  
Footnotes and references

MRI=magnetic resonance imaging; VZV=varicella zoster virus

  1. MAVENCLAD™ Product Monograph. EMD Serono. November 2017.

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