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Monitoring

MAVENCLAD™’S MONITORING INCLUDES PRETREATMENT SCREENING AND PERIODIC MONITORING OF LYMPHOCYTE COUNTS1

Monitoring Lymphocyte

Lymphocyte counts must be:

  • Normal before initiating MAVENCLAD in year 1
  • At least 800 cells/mm³ (i.e., Grade 0 or 1) before initiating MAVENCLAD in year 2

The treatment course in year 2 can be delayed for up to 6 months to allow for lymphocyte
recovery. If recovery takes more than 6 months, the patient should stop taking MAVENCLAD.

Should lymphocyte counts drop below 500 cells/mm³, active monitoring is recommended until values increase above 500 cells/mm³.

Screening prior to treatment initiation:

Monitoring Screening

Learn more about MAVENCLAD

 

Demonstrated efficacy

MOA

Safety and tolerability profile

  

 

Explore MAVENCLAD’s efficacy.

Learn more

Understand MAVENCLAD’s MOA.

Learn more

Learn about MAVENCLAD’s safety and
tolerability profile.

Learn more

  
Footnotes and references

MRI=magnetic resonance imaging; VZV=varicella zoster virus

  1. MAVENCLAD™ Product Monograph. EMD Serono. November 2017.

© 2019 EMD Serono. All rights reserved.
MAVENCLAD™ is a trademark of Merck KGaA, Darmstadt, Germany.

Importer & Distributor:
EMD Serono, A Division of EMD Inc., Canada
A business of Merck KGaA, Darmstadt, Germany
2695 North Sheridan Way, Suite 200
Mississauga, Ontario  L5K 2N6 Canada

If your patients experience any side effects, they should talk to their doctor, pharmacist or nurse. This includes any possible side effects not listed in the package insert. Side effects can also be reported directly via the Health Canada website at www.healthcanada.gc.ca/medeffect, by calling the Regional Adverse Reaction Centre at 1-866-234-2345 or by contacting the adveva team at 1-888-677-3243.

CA/CLA/0318/0013E

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